What does the lock and key hypothesis state?
The key (substrate) fits perfectly in the lock (enzyme). The lock and key hypothesis states that the substrate fits perfectly into the enzyme, like a lock and a key would. This is in contrast with the induced fit hypothesis, which states that both the substrate and the enzyme will deform a little to take on a shape that allows the enzyme to bind the substrate. Since, the substrate binds to a specific enzyme, this hypothesis is meant for the substrate specific enzymes.
A temporally resolved DNA framework state machine in living cells
Lock and Key model
Photo- and Redox-Driven Artificial Molecular Motors
Lock and Key Model- Mode of Action of Enzymes
The concept of a 'predisposed' free energy landscape.
SOLVED: Fischer lock and key hypothesis
The induced fit hypothesis and lock and key hypothesis of enzymes
Lock and Key Model Key Points and Limitations
The Lock and Key Model Enzyme Explained!
What do the lock and key hypothesis state?
What evidence is there that the lock and key model is not true for enzyme specificity? - Quora
Tuto (SAQ), PDF, Adenosine Triphosphate
