In a recent bioRxiv paper, a research group from the Marinomed Biotech biopharmaceutical company in Austria showed that a sulfated polysaccharide iota-carrageenan has the propensity to inhibit cell entry of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by using an in vitro neutralization assay.
A Highly Potent SARS-CoV-2 Blocking Lectin Protein
Inhibitory Effect of Iota-carrageenan on Porcine Reproductive and Respiratory Syndrome Virus in Vitro - Chunhe Guo, Zhenbang Zhu, Piao Yu, Xiaoxiao Zhang, Wenjuan Dong, Xiaoying Wang, Yaosheng Chen, Xiaohong Liu, 2019
Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Postexposure Prophylaxis of COVID-19 in Hospital Personnel Dedicate
Exploring algae and cyanobacteria as a promising natural source of antiviral drug against SARS-CoV-2 - ScienceDirect
Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs
Full article: Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Postexposure Prophylaxis of COVID-19 in Hospital Personnel Dedicated to Patients Care with COVID-19 Disease
Small molecules in the treatment of COVID-19
Frontiers Iota-Carrageenan Prevents the Replication of SARS-CoV-2 in a Human Respiratory Epithelium Cell Line in vitro
Iota-carrageenan from red seaweed inhibits SARS-CoV-2 in laboratory conditions
A study protocol for a double-blind randomised placebo-controlled trial evaluating the efficacy of carrageenan nasal and throat spray for COVID-19 prophylaxis—ICE-COVID, Trials
Iota-carrageenan extracted from red algae is a potent inhibitor of SARS‐CoV- 2 infection in reconstituted human airway epithelia - ScienceDirect
IJMS, Free Full-Text
Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro
Carrageenan - an overview
Frontiers Carrageenan From Kappaphycus alvarezii (Rhodophyta, Solieriaceae): Metabolism, Structure, Production, and Application